While gene editing is already utilised to develop new treatments, researchers now suggest that it can even help in slowing down ageing. Scientists in the US have found a novel gene-editing therapy, which slows down ageing in mice with progeria syndrome, which is a rare genetic disorder that also afflicts humans.
Ageing is the main risk factor for a variety of health conditions such as heart disease, cancer and Alzheimer’s. This raises the demand for anti-ageing therapies.
[Higher levels of tau, a toxic brain protein linked to brain damage and cognitive decline, has been seen in sleep-deprived adults]
According to the scientists from the Salk Institute in the US, a novel CRISPR/Cas9 genome-editing therapy can suppress the accelerated ageing observed in mice with Hutchinson-Gilford progeria syndrome.
The study findings published in the journal Nature Medicine gives insights into the molecular pathways involved in accelerated ageing, and how to reduce toxic proteins via gene therapy.